The Queen-Regent was enraged through all her despotic Spanish haughtiness at such resistance. She tried to step in by the arrest of the foremost members of the Opposition, but failed, and only provoked violent tumults. The young Prince of Conde, coming home from Germany flushed with victory, hated Mazarin extremely, but his pride as a Prince of the Blood, and his private animosities impelled him to take up the cause of the Queen. She conveyed her son secretly from Paris, and the city was in a state of siege for several months. However, the execution of Charles I. in England alarmed the Queen on the one hand, and the Parliament on the other as to the consequences of a rebellion, provisions began to run short, and a vague hollow peace was made in the March of 1649.

Conde now became intolerably overbearing, insulted every one, and so much offended the Queen and Mazarin that they caused him, his brother, and the Duke of Bouillon, to be arrested and imprisoned at Vincennes. His wife, though a cruelly-neglected woman whom he had never loved, did her utmost to deliver him, repaired to Bordeaux, and gained over the Parliament there, so that she held out four months against the Queen. Turenne, brother to Bouillon, and as great a general as Conde, obtained the aid of Spaniards, and the Coadjutor prevailed on the King's uncle, Gaston, Duke of Orleans, to represent that the Queen must give way, release the Princes, part with Mazarin, and even promise to convoke the States-General. Anne still, however, corresponded with the Cardinal, and was directed by him in everything. Distrust and dissension soon broke out, Conde and the Coadjutor quarrelled violently, and the royal promises made to both Princes and Parliament were eluded by the King, at fourteen, being declared to have attained his majority, and thus that all engagements made in his name became void.

Conde went of to Guienne and raised an army; Mazirin returned to the Queen; Paris shut its gates and declared Mazarin an outlaw. The Coadjutor (now become Cardinal de Retz) vainly tried to stir up the Duke of Orleans to take a manly part and mediate between the parties; but being much afraid of his own appanage, the city of Orleans, being occupied by either army, Gaston sent his daughter to take the charge of it, as she effectually did--but she was far from neutrality, being deluded by a hope that Conde would divorce his poor faithful wife to marry her. Turenne, on his brother's release, had made his peace with the Court, and commanded the royal army. War and havoc raged outside Paris; within the partisans of the Princes stirred the populace to endeavour to intimidate the Parliament and municipality into taking their part. Their chief leader throughout was the Duke of Beaufort, a younger son of the Duke of Vendome, the child of Gabrille d'Estrees. He inherited his grandmother's beauty and his grandfather's charm of manner; he was the darling of the populace of Paris, and led them, in an aimless sort of way, whether there was mischief to be done; and the violence and tumult of this latter Fronde was far worse than those of the first.